Biotin impurity 32 CAS 22342-46-7(free base)
| CAS No. | 22342-46-7(free base) |
| Molecular Formula | C9H18N2O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Biotin impurity 32 (CAS 22342-46-7(free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C9H18N2O2SHBr and a molecular weight of 299.23 g/mol.
The molecular framework of Biotin impurity 32 (C9H18N2O2SHBr) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H18N2O2S HBr |
| Molecular Weight | 299.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Biotin Standards
- Biotin-PEG4-amide-Alkyne (CAS 1006592-45-5)
- Biotin-PEG4-Amide-C6-Azide (CAS 1006592-62-6)
- Biotin-PEG2-C4-alkyne (CAS 1011268-28-2)
- Biotin-PEG2-C6-azide (CAS 1011268-29-3)
- Biotin EP Impurity F (CAS 101469-35-6)
- Biotin 4-amidobenzoic acid sodium salt (CAS 102418-74-6)
- Biotin-4-Fluorescein (CAS 1032732-74-3)
- Biotin Impurity 1((+)-Biotin (+)-Sulfoxide) (CAS 10406-89-0)
Recommended Standards
- Tryptophan impurity 40 (CAS CATO-C4X-137340)
- Celecoxib Impurity 30 (CAS 2356153-95-0)
- Oseltamivir Impurity 130 (CAS CATO-C4X-1720130)
- 2-(Difluoromethyl)-4-hydroxy-3-(trifluoromethoxy)pyridine-6-carboxylic acid (CAS 1803960-46-4)
- Sunitinib Impurity 86 (CAS 90433-88-8)
- Chloro(2'-amino-1,1'-biphenyl-2-yl)palladium(II) dimer, min. 847616-85-7 BIS[2'-(AMINO-KAPPAN)[1,1'-BIPHENYL]-2-YL]-KAPPA;CHLORO(2'-AMINO-1,1'-BIPHENYL-2-YL)PALLADIUM(II) DIMER;DI-MU-CHLOROBIS(2'-AMINO-1,1'-BIPHENYL-2-YL-C,N)DIPALLADIUM(II);DI-MU-CHLOROBIS[2'-(AMINO-N)[1,1'-BIPHENYL]-2-YL-C]DIPALLADIUM(II);Chloro(2'-amino-1,1'-biphenyl-2-yl)palladium(II) dimer, min. SC10587 (CAS 847616-85-7)
- N-methyl-1-(5-(1-methyl-1H-pyrazol-3-yl)isoxazol-3-yl)methanamine (CAS 1174870-35-9)
- 2-((1-(2,5-Dichlorophenyl)ethyl)amino)propan-1-ol (CAS 1155572-71-6)
- 4-(3-Fluorophenyl)-1-methyl-1H-imidazol-5-amine (CAS 1250735-88-6)
- Glucagon-like peptide 2 (CAS 89750-15-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com